Middleton is a city in Essex County, Massachusetts, USA. The status of the city was assigned in 1728, the population in 2010 was 8987 people.
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Middleton, covering an area of about 14 square miles (37.3 km²), is located in Essex County, Massachusetts, about 37 km from Boston. The city is bordered by Danvers to the east, Topsfield, Boxford and North Andover to the north, North Reading to the west and Peabody to the south.
Middleton is connected to Lawrence northwest by Highway 114. Interstate 95 runs east of the city. The Ipswich River flows through Middleton